1) Explain the importance of the cytochrome P-450 enzyme intoxicant biotransformation.
P-450 Enzyme
Biotransformation enzyme or medication utilizing chemicals assumes a unique part in the
digestion of remote and endogenous mixes. There are two principle gatherings of
biotransformation chemicals. The main conference changes over hydrophobic mixes into more
active metabolites by uncovering or including practical conventions. Among different catalysts,
this discussion contains oxidative chemicals like the cytochromes P450 and the flavin
monooxygenases, and also hydrolytic compounds like esterases and amidases. The second
conference is made out of catalysts that catalyze the conjugation of these functionalized mixes to
a water-dissolvable moiety. A portion of the proteins required for stage II digestion is UDP-
glucuronosyltransferases, sulfotransferases and glutathione S-transferases. The subsequent
conjugates can then be discharged out of the body (Montellano, 2015)
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