First, do some research on how the amygdala, hippocampus, and prefrontal cortex communicate and result in normal behavioral response. You will begin your reading on the amygdala by following this link. After reading this section, click on several other structures in the brain at the end of the page to read about the interactions between these three regions. Briefly describe this pathway and the behavior that results from the interaction of these regions using 2-3 sentences. This will help you to introduce the content that you will address in the sections below.
Body Paragraph 1 Summarize the effects of glucocorticoids on the hippocampus and prefrontal cortex reported in the article How to Prevent Stress from Shrinking Your Brain. Body Paragraphs 2 and 3 What effect on hippocampal cells have stress hormones had in recent studies described by Stress Effects on Structure and Function of Hippocampus? What effect have they had on the amygdala in studies?
What are the implications of these effects? HINT: What are the functions of the regions and how might they be affected by changes in their structure? Body Paragraph 4 What is neurogenesis and where does it occur in the brain? What effect on the regeneration of hippocampal cells is reported in this article? What is the mechanism? Conclusion Paragraph 1 Summarize the effects of cortisol on this pathway by describing how PTSD can result from perpetuated cortisol release and how this can result in depression by activating and/or reinforcing depression pathways. Conclusion Paragraph 2 Describe the methods proposed to counteract the negative effects of chronic stress in How to Prevent Stress from Shrinking Your Brain.
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